Reaper does generate a checksum when rendering to DDP.
Here's the changelog.
v4.25 - July 12 2012
+ DDP support: improvements (MD5, CD-TEXT support, UTF-8/ascii conversion)
DDP (Disc Description Protocol) is widely accepted now by most pressing plants as the industry standard.
Here's a simple description by Mastering Engineer Bob Katz
Scroll down to the DDP section.
http://www.digido.com/audio-faq.html