Make sure you have all 16 channels selected in Reaper. In the audio device settings window in Reaper make sure you have your first input selected as the first and the last (16) selected as you last.
I am assuming you are using an ASIO driver. In the audio device settings window I mentioned before click on the "ASIO configuration" button. I do not know the ZED driver software, but it is possible that you can rout the signals between the board and reaper in this software. Clicking on that button should open up the ZED's software interface.
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