There is a lack of option to interact with send or insert butons inside mixer panel, for exemple.
It could be good, if we can choose mute the FX plug or open the plug inside FX window with double click on insert buton ...
It could be interesting if we can set the volume fader to 0 with right click + Ctrl or middle click + alt ...
etc.
To vote :
http://forum.cockos.com/project.php?issueid=4117