Since some time (supposedly since the update to Kontakt 6.0) I have a similar issue:
I use a Kontakt instance with an instrument bank.
Sometimes the pan of one of the instruments is mysteriously set to full left or to full right. It's not always the same instrument, but different ones had been affected. I don't know when this happens, I found it after loading the project, and it's saved within the project so the next prjoiect load results in the same.
As I don't have the full Kontakt version, I can't peer in the parameters of the instruments that are in an instrument bank, so I can't "see" the issue. When dropping the same instrument again in the same place in the bank, it's back to normal. Now I can save the Reaper project, and with the next load it's OK again.
In the instruments loaded in the bank, none has a dedicated "automation Parameter" assigned to or a CC "learned" to pan, while mltiple other instrument parameters are assigned to CCs (for Live playing) and a lot of Midi is flying around in the FX chain.
-Michael
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