No help here, and only Windows user, BUT .... have been running Windows 10 Pro 64-bit (Insider Preview) for a few weeks. No issues so far with Reaper 4.78 and also ran a bit with V5.0xx. Also running all Spectrasonics (no NI), IvoryII, XLN, Jamstix3, and all seem solid.
Good luck with your timing and dual boots !
Thom B
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