I tried that a few years ago after reading the same things. Reaper was clearly snappier with OSX. However, it was Windows XP I tried at that time and I didn't do any tweaking. I see more comments that claim the opposite - Windows having faster GUI response.
My focus is audio so I'll take any GUI lags vs losing stability if that's the case now. And I'm just not going to buy a newer Windows install for an experiment. If I had some Windows only plugin that I just had to demo, I'd launch the Windows version of Reaper with Wine in OSX.
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