For wine, use synaptic to uninstall whatever wine is installed,
then follow the guide at the link to set up the ppa for wine,
and install the newest wine stable, or wine-staging. I followed
the steps yesterday, and wine-staging 2.11 is working as expected.
https://wiki.winehq.org/Ubuntu
The next link has official wine configuration tips:
https://www.winehq.org/docs/wineusr-...nfig-wine-main
I've not changed many Reaper default settings, myself.
In the Buffering-FX processing/multiprocessing settings panel,
in the 'Anticipative FX processing' area, I enabled
Allow on tracks without FX
Allow live FX multiprocessing on _x_ CPU's.
A supported nVidia videocard will be good to have for using
commercial plugins with complex gui's
Cheers