I've played around with Rewire a bit, and the performance is as bad as it was when I was routing midi from one tab to another in the same project. If I have three tracks with VSTis enabled in the Rewire slave, then CPU load just gets too high and I get clicks and pops. With the same VSTis in a single project the CPU is much lower.
The other limitation appears to be that as far as I can tell, there is only one Rewire bus available, so only 16 MIDI channels and 32 audio channels are available.
I'm going to get a trial version of Vienna Ensemble Pro and see if that performs better.
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