An expander could help.
Also a low-pass filter (part of the reason high gain amps don't sound quite so nasty in real life is because the high frequencies don't make it out of the speakers).
At the end of the day, there's just no way to decouple distortion from noise. Gates, expanders and good ol' fashioned editing are your weapons of choice unless you can live with the compromise of messing with your tone by using ReaFIR.
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