Trilian does not work at all. Now, that's a big issue. For me at least.
I'm a pro Logic user, and I can't buy/switch to Reaper if major plugins are not usable.
I think Reaper is a super DAW. I love it. I just hate the "FX" interface,
The midi engine needs to "groove" and work as well as Logic, and Audio has to be as well as PT to really emerge.
My 2 cts.