When does the noise appear ? when listening to your dry or wet guitar input, or both ?
Also note that the guitar mics are sensitive to electro magnetic fields, so maybe it's coming from your guitar. Sometimes by changing place in the room, or whanging where the mics are pointing to, some of the "perturbations" disappear.
And when recording a distorted guitar, it's better to have a gate, to remove the noise coming from the guitar mics. Every distorted guitar have a buzz noise if not gated.
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