If I had to choose a single virtual amp for Rock/Metal, it would be the UAD Marshall Plexi. It's stunning. Brainworx also have some excellent Orange Amp Models (not official, but they sound fantastic).
With much more processing, almost any modern VST can work with the right settings. I used a Line 6 Hd500 to record guitar parts for this song (a desperate times, desperate measures situation and it did need processing like a generous low pass filter). But I think it worked surprisingly well
https://open.spotify.com/track/1wlcR...7cf13a4f1e4cc7