For the record, Im running OCLP here to allow Monterey on my 2013 iMac. You may want to look into that as well. I have zero issues with it here.
Sierra is OLD bro, Im surprised Reaper still works on it to be honest and especially any plugins
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Reaper 4.78 12.6.6 Monterey
2013 iMacPro
Steinberg MR816X. Apollo Twin Solo
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