Hi,
I'm having some weird problem with monitoring the sound on Reaper. On stereo, each channel sounds different. When I pan, I can hear that the right channel sounds like it's lower in quality (cutting off some low sounds) and the left channel sounds like it has more bass in it. I've tested this on multiple different audio files and it seems to be persistent.
I've tested my speakers/headphones on other audio editing software and they sound just normal. This problem seems to happen only in Reaper. Even when I render out a file from Reaper, it sounds normal. I can even see the volume monitors look normal, so I know that the problem lies in listening to audio previewed off Reaper. This would be fine, but since I have to work with binaural audio, it really hinders my work.
There's an active Monitoring FX chain indicated at the top right corner which might be causing issues. So check the plugins in there (View > Monitoring FX).