Opening Plugin GUI Audio noise

[pepe44]

Hi all.
I´m posting here on live section because its a thing that can bother some of you too.

I recently prepared a session for live use, very simple , 10 tracks for recording and one of them has antares auto-tune access ( zero samples and cpu efficient). So far so good.
The "problem" arises every time i try to open the auto tune GUI for some changes (im not using automation for key changes because with this artist is not always the same set list) . There is a little buffering thing going on, a small audio burst just by opening the plugin and this on a arena with a large P.A system is t-e-r-r-i-b-l-e.

I´m using a Lenovo laptop 320 ideapad , i7 16G RAM DDR4- The mixer is a x32 rack which serves has audio interface too. ( I have a clean vocal channel and making that channel going to reaper for auto tune and coming out to another mixer channel) Like this i always keep a clean , unprocessed vocal track if needed.
The X32 audio interface is set to 128 Buffer size and i have a 5.6ms latency roundtrip which is ok for the artist IEM.

The only solution i found is leaving the Auto tune GUI open while running the show.
Anyone with some "solution" , Reaper preferences to make the GUI opening whitout that noise?

Thanks.